This paper is an analysis of surgical wound infection according to the type of operation and bacteria involved, based on a study of 2, 080 operations performed at Department of Surgery, Yonsei University College of Medicine during the period of Jan. to Dec. 1975.
Modified National Research Council Definitions and Classification, were used for postoperative wound infection. The overall infection rate among 2,080 cases was 5.1%. The incidence of postoperative wound infection in 1,128 cases of "Clean" operation (Group I) was 1: 41% and in .818 cases of Clean-contaminated operation (Group II) was 6.9% and 134 cases of "Contaminated" operation (Group III) was 26.12%. There were remarkable high rate of wound infection in the cases those who had contaminated operation. The infection rate was higher in male than female. Increase in the rate of infection occurred in old age.
The bacterial cultures from 99 cases of postoperative wound infection are, consisted of 12 cases of negative culture, 36 cases of single organism, and 51 cases of mixed organisms 164 organisms of 15 species of bacteria were isolated from 77 cases of positive culture. The bacteria strains are consisted of 34(20.3%) strains of gram (+) bacteria and 129 (79.7%) of gram In cases of mixed infection only 2 cases, were pure gram (-t-) bacteria mixed infection and 28 cases in. Group II and III were pure gram (-) mixed infection.
Staphyllococeus coag. (+) was : the most common pathogen isolated following Group I and Coliform bacili were, the most common organism in Group II and III, 140, strains of cultured, organism were performed sensitivity test with Ampicillin, Chioramphenicol, Lincomycin, Tetracycline, and Carbenicillin for gram (+) organism, and Ampicillin, Kanamycin, Chloramphenicol, Streptomycin, , Tetracycline, and Gentamycin for gram (-) except Pseudomonas.
In antibiotic sensitivity of gram (+) organism, more effective antibiotics were Carbenicillin, Cloxacillin and Lincomycin and gram (-) were Gentamycin and Chloramphenicoi Pseudomonas was responded for Carbenicillin, Colymyein and Gentamycin in order of efficacy.
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